Screening Marker Components Of Tyrosinase Inhibitor From Xylocarpus Granatum Stem
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چکیده
منابع مشابه
Novel and Neuroprotective Tetranortriterpenoids from Chinese Mangrove Xylocarpus granatum Koenig
Eight new tetranortriterpenoids (1-8) were isolated from the twigs and leaves of the Chinese mangrove plant Xylocarpus granatum, together with four related known ones (9-12). The structures of new compounds were elucidated by detailed spectroscopic analysis. The absolute configuration of 9-epixylogranatin A (1) was determined by time-dependent density functional theory-electronic circular dichr...
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a Department of Medicinal Natural Product Chemistry, School of Pharmaceutical Sciences, Hebei Medical University, 361 Zhongshan East Road, Shijiazhuang, 050017, Hebei Province, P. R. China. E-mail: [email protected] b College of Basic Medicine, Hebei Medical University, 050017, Shijiazhuang, P. R. China. E-mail: [email protected] c North China Pharmaceutical Group Corporation, New D...
متن کاملChamigrane Sesquiterpenes from a Basidiomycetous Endophytic Fungus XG8D Associated with Thai Mangrove Xylocarpus granatum
Six new chamigrane sesquiterpenes, merulinols A‒F (1‒6), and four known metabolites (7‒10) were isolated from the culture of the basidiomycetous fungus XG8D, a mangrove-derived endophyte. Their structures were elucidated mainly by 1D and 2D NMR, while the structures of 1 and 2 were further confirmed by single-crystal X-ray diffraction analysis. The in vitro cytotoxicity of all compounds was eva...
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Protoxylogranatin B, a new protolimonoid identified from the seeds of a Chinese mangrove, Xylocarpus granatum, was proposed as the key biosynthetic intermediate. Its structure was established on the basis of spectroscopic techniques, including 1 H– 1 H COSY, HSQC, HMBC and NOESY spectra. The finding of this compound suggested an oxidative cleavage biogenetic pathway from protolimonoid to limonoid.
متن کاملTyrosinase inhibitor activity of coumarin-resveratrol hybrids.
In the present work we report on the contribution of the coumarin moiety to tyrosinase inhibition. Coumarin-resveratrol hybrids 1-8 have been resynthesized to investigate the structure-activity relationships and the IC(50) values of these compounds were measured. The results showed that these compounds exhibited tyrosinase inhibitory activity. Compound 3-(3',4',5'-trihydroxyphenyl)-6,8-dihydrox...
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ژورنال
عنوان ژورنال: Jurnal Kimia VALENSI
سال: 2012
ISSN: 2548-3013,2460-6065
DOI: 10.15408/jkv.v2i3.111